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Reduz também o risco de perisitência de vírus de alto grau oncogênico.

Foi utilizado PCR para detecção de DNA de HPV em raspado de glande. Trabalho excelente e original feito no Kenya.

Leia mais:

J. Infect. Dis 2014 Sep 26;[EPub Ahead of Print]:

Acquisition and Persistence of Human Papillomavirus 16 (HPV-16) and HPV-18 Among Men With High-HPV Viral Load Infections in a Circumcision Trial in Kisumu, Kenya
1. Virginia Senkomago 1,
2. Danielle M. Backes 1,4,
3. Michael G. Hudgens 2,
4. Charles Poole 1,
5. Kawango Agot 7,
6. Stephen Moses 8,
7. Peter J. F. Snijders 9,
8. Chris J. L. M. Meijer 9,
9. Albertus T. Hesselin 9,
10. Nicolas F. Schlecht 5,
11. Robert C. Bailey 6
12. Jennifer S. Smith 1,3

+Author Affiliations

1. 1Department of Epidemiology
2. 2Department of Biostatistics, Gillings School of Global Public Health
3. 3Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill
4. 4Department of Epidemiology, Brown Public Health, Brown University, Providence, Rhode Island
5. 5Department of Epidemiology and Population Health, Albert Einstein College of Medicine, New York, New York
6. 6Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois, Chicago
7. 7Impact Research and Development Organization, Kisumu, Kenya
8. 8Centre for Global Public Health, University of Manitoba, Winnipeg, Canada
9. 9Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands
1. Correspondence: Virginia Senkomago, PhD, MPH, Department of Epidemiology, University of North Carolina, 135 Dauer Drive, 2101 McGavran-Greenberg Hall, CB #7435, Chapel Hill, NC 27599 (epi.senkvirg@unc.edu).
1. Presented in part: 28th International Papillomavirus Conference, San Juan, Puerto Rico, November 2012.

Abstract

Background. Circumcision and lower human papillomavirus (HPV) viral loads in men are possibly associated with a reduced risk of HPV transmission to women. However, the association between male circumcision and HPV viral load remains unclear.
Methods. Swab specimens from the glans and shaft of the penis were collected from men enrolled in a circumcision trial in Kisumu, Kenya. GP5+/6+ polymerase chain reaction (PCR) was used to identify HPV DNA types. HPV-16 and HPV-18 loads were measured with a LightCycler real-time PCR and classified as high (>250 copies/scrape) or low (≤250 copies/scrape).
Results. A total of 1159 men were randomly assigned to undergo immediate circumcision, and 1140 men were randomly assigned to the control arm (these individuals were asked to remain uncircumcised until the study ended). The hazard of acquisition of high-viral load infections in the glans was lower in the circumcision arm, compared with the control arm, for HPV-16 (hazard ratio [HR], 0.32 [95% confidence interval {CI}, .20–.49]) and HPV-18 (HR, 0.34 [95% CI, .21–.54]). The 6-month risk of HPV persistence among men with high-viral load infections in the glans at baseline was lower in the circumcision arm, compared with the control arm, for HPV-16 (risk ratio [RR], 0.36 [95% CI, .18–.72]) and HPV-18 (RR 0.34 [95% CI, .13–.86]). Weaker and less precise results were obtained for shaft samples.
Conclusions. Male circumcision could potentially reduce the risk of HPV transmission to women by reducing the hazard of acquisition, and the risk of persistence of high-HPV viral load infections in the glans in men.

Key words

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A primeira dose de vacina contra HPV teve cobertura de 96% (meninas de 11 a 13 anos). Mas, as taxas na dose 2 estão BAIXÍSSIMAS.

É preciso que TODOS tenham atitudes.

A aula do professor Edson Moreira, Fiocruz Salvador, no HPV In Rio 2014, pode, também, ajudar no entendimento de problemas.



Leia mais: Nova vacina para HPV final de 2014

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Reações adversas em Vacina de HPVApós mais de 5 milhões de doses da vacina quadrivalente contra HPV serem aplicadas em meninas de 11-13 anos, no Brasil, foi recentemente noticiado, pela imprensa, que algumas meninas apresentaram efeitos adversos envolvendo, até, internação hospitalar. Trata-se de um quadro emocional (ansiedade) relacionado a vacinações em geral.

O Programa Nacional de Imunização emitiu nota de esclarecimento concluindo que a vacinação não será interrompida.

Leia a nota do Ministério da Saúde do Brasil, na íntegra, em:

Nota Informativa 106:  vacinacao contra HPV vigilancia EAPV

 

Aproveitamos para divulgar importante documento do CDC – USA sobre vacinação contra HPV:

Recommendations of the Advisory Committee on Immunizatio Practices (ACIP)

 

 

 

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Guia de Pergunta e Respostas para Professional de Saúde

Sumário Guia Prático sobre o HPV

1 ENTENDA O QUE É O HPV
2 CONTÁGIO
3 DIAGNÓSTICO
4 RELAÇÃO HPV E CÂNCER
5 PREVENÇÃO
6 VACINAÇÃO
7 INFORMAÇÕES PARA PROFISSIONAIS DE SAÚDE
8 REFERÊNCIAS BIBLIOGRÁFICAS

Baixe uma cópia do PDF aqui

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HPV-2014       PDF: HPV-2014